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| Advanced Multiple Sclerosis:Complications and Caregivers A small proportion of people with primary or secondary progressive MS eventually develop symptoms and disabilities that require skilled care and special equipment. Some of those individuals with very severe MS will experience a somewhat shortened lifespan. This is almost always due to a complication, such as overwhelming infection, skin breakdown, or malnutrition. Avoiding such complications will maximize the person's health, quality of life, and ability to function. |

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| Chemical Messenger Inactivates Cellular "Police" in Multiple Sclerosis One of the fundamental mysteries of autoimmune diseases is how normally protective immune responses go bad. A new study sheds some light on this issue by showing that a chemical messenger called interleukin 12, or IL-12, allows some white blood cells to proliferate and damage healthy tissues. This finding may lead to new drug treatments for multiple sclerosis (MS) and other autoimmune diseases. Released: Friday, October 28, 2005 |

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| Deep Brain Stimulation for Movement Disorders Deep Brain Stimulation for Movement Disorders. Information from the Cleveland Clinic, ranked one of the top four hospitals in the nation by U.S. News and World Report.2005. |

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| Epstein-Barr Virus Might Kick-Start Multiple Sclerosis Researchers have found that patients with multiple sclerosis (MS) carry a population of immune cells that overreact to Epstein-Barr virus. The virus, which causes mononucleosis and may contribute to some cancers, has long been suspected to play a role in MS. However, the mechanism linking the virus to the disease was poorly understood. |

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| FDA Allows Clinical Studies of Tysabri (natalizumab) for Treatment of MS to Proceed The Food and Drug Administration (FDA) is reporting that Biogen-IDEC and Elan Corporation announced yesterday that FDA removed the clinical hold on Biogen-IDEC's studies of Tysabri (natalizumab) for patients with multiple sclerosis. This will allow clinical trials to go forward. In February 2005 Biogen-IDEC had announced suspension of marketing and clinical trials after three patients developed progressive multifocal leukoencephalopathy (PML), a frequently fatal infection of the brain, two following treatment with natalizumab for MS, and one patient being treated for Crohn's Disease. Two of these cases were fatal. |

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| Glossary of MS Terms Glossary of MS Terms (National Multiple Sclerosis Society) |

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| Hormones and Multiple Sclerosis Does pregnancy affect MS-related disability? If the number of relapses during the third trimester is reduced by 71%, what about the effect of pregnancy on the accumulation of disability? Does pregnancy ultimately slow down the onset of disability? |

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| Intimacy and Multiple Sclerosis Intimacy and Multiple Sclerosis (Cleveland Clinic Foundation) |

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| JAMA Patient Resources Page on Multiple Sclerosis (MS) JAMA (the Journal of American Medical Association) Patient Resources Page on Multiple Sclerosis (MS). |

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| Lab Test Online UK Multiple Sclerosis A public resource on clinical lab testing from the laboratory professional who do the testing. |

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| Living With MS Treatment Locations A list of clinical facilities have a formal affiliation with the National MS Society. The appropriate chapter clinical advisory committee, composed of MS experts, has reviewed and approved the affiliation. |

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| MedlinePlus: Multiple Sclerosis Multiple Sclerosis information from the National Institutes of Health MedlinePLUS. |

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| MS and Pregnancy Personal stories about childbirth, interviews with healthcare professionals, updates on genetics, answers to frequently asked questions, a helpful pre-postpartum checklist, a discussion on breastfeeding, the disease-modifying drugs, and more. |

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| MS Society UK The MS Society is the UK's largest charity for people affected by Multiple Sclerosis (MS) - about 85,000 people in the UK. |

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| Multiple Sclerosis (Patient Education Institute) Interactive Tutorial Multiple Sclerosis (Patient Education Institute) Interactive Tutorial |